Two days ago,

I had a "3 in 1" with someone I love at KL,

why called it 3 in 1? Because we enjoyed 3 activities in a day,

so I formulated the long words into short words, which named as "3 in 1".

Firstly, we went to Pavillion for the most romantic Swaroski merry-go-round ride,

then take a stroll via the bridge to Grand Hyatt hotel, Thirty8 Restaurant,

the country fine dining of Malaysia,

then the last stage, we went to Lavish Spa for simple soaking.

This is the most contented and glamorous ride that I have ever rode in my life,

the spinning trojan and carriage are made of Swaroski diamond and crystal,

it's absolutely fulfilled my partial materialistic life, and make me to become a day "High Maintenance Woman".

The formal navy dress and watch are instantaneously matching the merry-go-round theme,

when the trojan spinning, we were taking selfie, playing happily and beautifully enjoyed our precious time.

Thirty8 Restaurant,

we had a great fine dining experience there with the super parallel twin tower view,

we ordered one prawn main course and salmon fillet main course respectively, and the signature desserts and a pot of Oolong Tea,

but apparently it looked like an English Flat White rather than a tea due to the inappropriate cup.

the price is affordable, we managed to merely eat up for RM287 :)

But the worst thing is we reckoned that the foods weren't fresh at all,

we both have diarrhea after the meal.

Lavish Spa, I don't feel really nice of it,

so I don't take much pictures besides than a selfie,

it's more like paying a few tenth dollar to "Tiara".

Sunday??!!

It has been my favorite day for 24 years.

Today's diary is....

I woke up in the late morning;

I had a hazelnut coffee with the beautiful 37th floor city-view,

the weather is too warm today at 24 degree celcius,

me and my housemates were all sweating at home,

thus I decided to go to the mall and cool down my body temperature,

at least there are air conditioning everywhere.

Firstly,

I went to Emporium Ting Dai Feng, had my late lunch,

then I loitered all the floors in the mall, 

from one mall to another mall, and from 4th floor to the basement,

I went to Salvatore Ferrangamo, Ralph Lauren, Dior, YSL and Alexander Hill high-end fashion shop lots in the mall,

and street brand Dotti fashion store in Melbourne Central.
And yay! I bought this,

my first black lace dress for Chinese New Year.

So,

this is the summary of my Melbourne's Sunday :)

Once again,

another semester had just over,

finally I've find some time to blogged before flying back to Malaysia.

It's a good idea to summarized everything instead of posting many individuals posts!

Here we go, 

this is what happened after my final examination life,

nothing else - ate, sleep, playing game, hang-out with buddies and reunion sleepover.

Today, we went to Dimsum buffet at Shang Hai Dynasty Restaurant,

it's only cost $29.90 per head! And we could grab anything we wish, except beer!

There are assorted foods awaiting us from the dim-sum trolley,

and made us ate until our belly ache.

One of the most important things that happened this morning was someone said me
"You come here to play Dim Sum or eat Dim Sum? Never eat at all, cost $29.90"

"Then I said I ate until very full already, because you came late, so before you came, I've eat a lot, and now my stomach really cannot fill in any more"

Then, the next second I said that,

the waitress pushed a trolley just behind of me, and asked

"Any desserts"
My unthinkable reaction made me reacted impulsively,

I enlarged my eyes and said
"Ah! Want want want, I want!"

OMG! Damn awkward,

everyone were laughing at me,

just said "my stomach really cannot fill anything already",

then the next second saying "want want want! I want desserts!"
(and was speaking that fast to the waitress)

Another funny thing is once I ordered,

I ordered all desserts from the tray,

4 different desserts - which are coconut jelly pudding, aloe-vera pudding, rose tea pudding & almond pudding.

Then, as I'm already fulled, and eating the high carbohydrate pudding,

I'm damn full and couldn't manage to swallow the last almond pudding,

then when one boy said
"Hey Clarissa, you dont want to eat that pudding already?"
Then I said
"Dont want already, my stomach almost burst already, you want give you lah"

Then I put the pudding onto the dining table,

then when he asked
"what flavour is this?"
Then I said

"Its almond pudding.... oh yeah I like almond, eh I want again, paiseh ya! 

*Everyone laughing damn loud for my kiddish hesitating behaviour.

Even me myself, also can't control my funniness but I'm absolutely serious!

I dont mean to create joke or embarrass myself,

but my contradict behaviours really make everyone laughed like hell.

The drug, a histone deacetylase inhibitor (HDACi), interferes with one of the ways that brain cells record memories, by precisely placing proteins called histones on certain segments of DNA, affecting which genes are expressed. The hope is that, using this principle, doctors could someday prescribe drugs that aid in the treatment of post-traumatic stress disorder (PTSD).

Right now, those seeking relief from PTSD typically use exposure therapy, in which a patient mentally revisits a traumatic memory in hopes of overcoming the anxiety associated with it. But "the options for treatment of PTSD are very limited. There's really no good medication, and exposure-based psychotherapy is often ineffective for older memories," says Li-Huei Tsai, the lead author of a new study documenting the research, published in the journal Cell. "This study suggests that mainuplating histone-based mechanisms involved in memory deserves a serious investigation, and could someday be applied to patients."

Exposure therapy usually involves intentionally re-experiencing stimuli associated with a traumatic memory in hopes of replacing the original memory with a new, harmless one. A war veteran experiencing PTSD, for instance, might put on a pair of virtual-reality goggles that portray a traumatic war experience, while consciously aware that he or she is safe in a therapist's office.

For relatively recent memories, this has been found to be relatively effective, in part because of the brain's natural neuroplasticity that allows it to replace associations. After a multi-year period of time, however, it seems that old memories harden, and can't be dislodged by new ones.

Interestingly, the same pattern has been observed in mice—and the use of an HDACi appears to be a way of lengthing the key period of neuroplasticity, which if it's able to be applied to humans could dramatically lengthen the time period for which exposure therapy is effective.

Researchers demonstrated this effect on neuroplasticity through trials in which mice were exposed to a brief electric shock just after hearing a loud tone, which forces them to associate the sound with a traumatic event. Normally, if the mice hear the same sound a day later without being shocked, they're able to replace the old memory with the new one, and will stop freezing up in fear when they hear the sound again. However, if a month passes before they listen to the sound again, the association between sound and pain is mentally cemented and permanent.

When the researchers examined activity going on at the molecular level, they noticed that the activity of histone proteins on DNA played a key role in the neuroplasticity that allowed the exposure to sound without a shock to dislodge very recent traumatic memories and replace them with new ones. This gave the researchers an idea: to use a drug like HDACi (currently used in research on cancer treatments) to artificially increase neuroplasticity for older memories by altering how histone proteins attach to DNA.

To do so, they exposed mice to the same tone-and-shock regimen, waited about a month without playing the tone, then injected them with an HDACi and tried to dislodge the memory with the same exposure treatment as before. This time, it worked. The mice didn't freezing up in terror when they heard the sound. On a cellular level, the researchers observed the same patterns that had normally only occured when day-old memories were replaced.

Obviously, humans are not mice, but previous research has suggested that the same principles related to neuroplasticity seem to apply to exposure therapy in both species. That's why the researchers suggest that combining an HDACi with conventional rexposure therapy could someday be a way to weaken the hold of older traumatic memories in people suffering from PTSD, replacing them with new memories devoid of anxiety.

"Persistent fearful memories are a problem very relavent to our society. A lot of people suffer from an inability to subside very traumatic events in their lives," Tsai says. "Combining this sort of treatment with exposure-based psychotherapy might eventually provide an option for them."

There are still a whole lot of hurdles to be cleared before this is a possibility. The MIT researchers—neuroscientists working in a rapidly emerging field called epigenetics, involving the regulation of gene expression—are attempting to answer basic questions about how the brain encodes memories. They're not researchers that develop drugs, so it'd likely be another team that carries the research forward, and it would first be necessary to prove that this sort of novel approach is safe for humans.

But it's worth noting that the researchers extended the mice's natural forgetting process, allowing the mice to replace a traumatic memory a month—rather than just a day—after it was formed. It's not as radical as Lacuna, Inc. magically erasing memories à la Eternal Sunshine, but it's also a lot more similar to the processes that already go on inside the brain, and therefore a much more realistic future treatment.

Phobia...?

Danger...?

Delusions...?

All of these mixed feeling came to me again,

I can't imagine that I just safely live for one or two years,

and the danger is coming soon.

I really scared, I can't imagine the hurts and pain would come to me when the time arrives,

I hate December, I'm afraid of December, especially the day after the last day of December,

I'm even afraid of next year,

I wish that she still who she is,

I wish that security can stay with me longer.

I'm afraid of smile, afraid of approaching,

afraid of hand, afraid of someone holding my wrist,

 afraid of being touched

afraid of bench, afraid of violence,

and afraid of those things that shouldn't be afraid.

I thought that I'm on the road of recovery as what she said,

but I guessed, when I perceived all these feeling,

I am not at all.

I experienced confusion, cold hands and feet, heart palpitation, severe nightmares and becoming mad recently.

I know, this day will still happen anyway.

Good bye bright world, hello my dull world.